Regulation of bioactive β-endorphin processing in rat pars intermedia

Influence of dopaminergic agents on beta-endorphin processing in rat pars intermedia.

Histological and histochemical studies on the rat pituitary pars intermedia.

Inspite of the recent progress in the endocrinology of the anterior pituitary, a specific part of the adenohypophysis which is in a close contact with the neurohypophysis, i.e., the pars intermedia, has been left in a state of incomplete understanding both in morphology and physiology. For example, early reports by ITANO (1936) and BAILLIF (1938) dealing with the rat pars intermedia, indicated ...

Pituitary Pars Intermedia Dysfunction - Diagnosis

Although the frequency of diagnosis and treatment of pituitary pars intermedia dysfunction (PPID) in horses has clearly increased over the past decade, there is no evidence that the prevalence of PPID is actually increasing. Increased recognition of the disease is likely a consequence of clients maintaining their horses to more advanced ages as well as improved health care (e.g., diet and denti...

Regulation of cancer progression by β-endorphin neuron.

It is becoming increasingly clear that stressful life events can affect cancer growth and metastasis by modulating nervous, endocrine, and immune systems. The purpose of this review is to briefly describe the process by which stress may potentiate carcinogenesis and how reducing body stress may prevent cancer growth and progression. The opioid peptide β-endorphin plays a critical role in bringi...

Pituitary pars intermedia dysfunction: equine Cushing's disease.

PPID in older equids has become a major health concern of horse owners. In response, equine practitioners have made greater efforts at understanding, diagnosing, and treating this disorder. Although PPID is recognized to be a different form of pituitary-dependent hyperadrenocorticism than is seen in canine or human patients, relatively little is known about the pathophysiology and natural progr...